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High throughput sequencing and molecular imaging technologies
marked the beginning of a new era for modern translational
medicine and personalized healthcare. The impact of having the
human sequence and personalized digital images in hand has also
created tremendous demands of developing powerful
supercomputing, statistical learning and artificial intelligence
approaches to handle the massive bioinformatics and personalized
healthcare data which will obviously have a profound effect on
how biomedical research will be conducted toward the improvement
of human health and prolonging human life in the future.
In spite of fast growing burgeoning research activity on
bioinformatics and computational molecular physics of living
matter, the basic problems in the field still remain unsolved.
For example, it is largely unknown how naturally evolved
proteins fold their 3-D structure with such functions involving
protein-ligand interfaces, molecular signaling, binding
efficiencies or protein - DNA interactions. Often it is hard to
rationally design drugs effectively as a result of virtually
intractable inherent complexity of bio-molecules. The
limitations of theoretical biology are real and serious but we
can examine or interrogate gene function and protein structure
in relation to the environment and available data, thus we can
infer the interactive context, structural and functional
information as a true collective personalized biomedicine that
acts synergistically with all information that are centered on a
particular type of disease on an individual human or patient.
The International Society of Intelligent Biological Medicine in
partnership with the International Journal of Functional
Informatics and Personalized Medicine (www.inderscience.com/ijfipm)
and the International Journal of Computational Biology and Drug
Design (www.inderscience.com/ijcbdd)
touches tomorrow's bioinformatics and personalized medicine
throughout today's efforts in promoting the research, education
and awareness of the upcoming inter/multidisciplinary field. The
development of methodologies in Functional Informatics and
Personalized medicine utilizes supercomputing, statistics
learning, and artificial intelligence in handling the
information and data from biomedical data sets, gene and protein
sequence information, patient's genotype, disease phonotype,
level of gene expression, lipidomics, and all available
biological and clinical information to discover the biological
mechanism of living organisms, stratify disease, design new
medication, planning a therapy, or initiate a preventative
measure that is particularly suited to that human or patient at
the time of administration. Advances of functional informatics
and personalized medicine make aim on the designing and
selection of exact treatment planning or exact right drug, at
exact right dose, to the exact right patient, at the exact right
time with exact minimum or no side effects. The benefits of
functional informatics and personalized medicine approaches
utilizing supercomputing and statistical learning are in its
"worry free" effectiveness, accuracy, efficacy, safety and speed
with exactly right prediction of prognosis. With progress in the
high throughput genome sequencing and digital images, biocomputing and medical research have unfolded a series of new,
predictive sciences that share the appendage -omics such as
genomics, proteomics, lipidomics, metabolomics, cytomics and
pharmaconomics. These have promoted new emerging computational,
statistical and biomedical approaches to drug design and drug
development as well as unleashing the potential of significantly
more accurate and more effective personalized diagnosis,
therapeutics, and patient care. The emerging high performance
computing, statistical learning and artificial intelligence
approaches will help discovering the disease variations and
developing new approach to disease prevention, treatment and
personalized healthcare.
The International Society of Intelligent Biological Medicine
(ISIBM) aims to use intelligent methods to study biological
medicine. The original idea to form this society came from the
organizers of IEEE 7th International Conference on
Bioinformatics & Bioengineering with 500 poeple gathered at
Harvard Medical, Boston, Massachusetts (IEEE BIBE 2007).
In the fields of bioinformatics, computational biology, and
bioengineering, scientists regularly approach important
biological and medical problems by using a common set of
intelligent methods, such as computational data mining,
evolutionary computation, pattern recognition, knowledge
representation, databases, combinatorics, stochastic modeling,
linguistic methods, robotics, string and graph algorithms,
constraint satisfaction, and parallel computation. With such a
plethora of intelligent methods, it is essential to provide a
platform to bring these scientists together to discuss
scientific issues in this fast growing field. ISIBM aims to fill
this need. The mission of ISIBM is to facilitate the
multidisciplinary development of intelligent methods and to
empower creative scientists in these fields to solve biological
and medical problems.
ISIBM is registered in the United States as a non-profit
academic / professional organization. To know more about the
society, please contact Secretary-General Prof. Michelle M. Zhu
(mzhu@cs.siu.edu
618-453-6057)
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